If you are sourcing 4-Ethylphenylboronic acid CAS 63139-21-9, the most important buying priorities are identity confirmation, purity documentation, packaging suitability, and dependable supply communication. I recommend treating this material as a research and synthesis intermediate rather than selecting it only by name or price. At Maison Chemical, we support B2B buyers by reviewing the required specification, confirming available documentation, and matching the order to the intended research, process-development, or manufacturing stage.
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4-Ethylphenylboronic acid is an aryl boronic acid containing an ethyl-substituted phenyl group and a boronic acid functional group. Its CAS number is 63139-21-9, and its commonly reported molecular formula is C8H11BO2, with a calculated molecular weight of approximately 149.98 g/mol. Because commercial specifications can differ in assay, water content, residual solvents, and packaging, buyers should request a current certificate of analysis before placing a production-oriented order.
This guide is intended for procurement teams, organic synthesis laboratories, pharmaceutical and agrochemical research groups, contract research organizations, and process-development departments. It is also useful for distributors that need a clearly identified aryl boronic acid from a responsive chemical supplier. The guidance applies whether you are purchasing a small evaluation quantity or qualifying a recurring source.
I have written this guide for buyers who already know the target compound or are comparing supply options. It does not replace your internal safety assessment, analytical method, or regulatory review. Instead, it provides a practical framework for asking the right questions before committing budget and project time.
4-Ethylphenylboronic acid is commonly considered a building block for carbon–carbon bond-forming chemistry, especially cross-coupling research such as Suzuki–Miyaura reactions. In these reactions, an aryl boronic acid may be combined with a suitable electrophilic partner under a compatible catalyst and base system. Actual conversion, selectivity, and work-up performance depend on the reaction design, substrate combination, catalyst, solvent, and operating conditions.
The para-ethyl substituent provides a defined structural feature for medicinal chemistry, discovery chemistry, and analogue preparation. It may be selected when a project requires an ethyl-substituted aryl fragment rather than unsubstituted phenyl or another alkyl-substituted alternative. Buyers should still confirm that the substitution pattern is correct, because positional isomers can have different CAS numbers and different synthetic value.
These are potential application areas, not guaranteed performance claims. Before scale-up, I recommend running a documented compatibility assessment with the intended reaction system and confirming the impurity profile that your downstream process can tolerate.
A buying decision should begin with a clear material specification. At minimum, compare the product name, CAS number 63139-21-9, molecular formula, molecular weight, assay requirement, appearance, and identification method. If your project is sensitive to trace impurities, add water content, residual solvents, inorganic residues, and relevant related substances to the request.
| Specification Area | Why It Matters | What to Request |
|---|---|---|
| Identity | Prevents substitution with a positional isomer or unrelated boronic acid. | CAS number, formula, molecular weight, and identification data. |
| Assay and purity | Supports reaction reproducibility and material accounting. | Current batch assay result and analytical method. |
| Physical description | Helps receiving teams identify obvious deviations. | Appearance, color description, and packaging condition. |
| Moisture and solvents | May affect weighing, reaction concentration, and process controls. | Water result and residual-solvent information where applicable. |
| Traceability | Supports qualification and repeat purchasing. | Batch number, manufacturing date, retest or shelf-life information, and COA. |
The molecular weight of approximately 149.98 g/mol is useful for stoichiometric calculations, but it should not be treated as evidence of purity. I advise buyers to compare the supplier’s reported value and formula with their internal records, then use the batch-specific COA for release decisions. If analytical data is not available before purchase, make its provision a defined quotation or order requirement.
First, identify whether the material is needed for feasibility screening, route development, pilot work, or routine production. A laboratory evaluation may prioritize a small pack and rapid availability, while a manufacturing program normally requires stronger batch consistency, traceability, and replenishment planning. The same compound can therefore require different commercial specifications at different stages.
Define the minimum acceptable assay and the critical impurities before comparing quotations. If the material enters a sensitive multi-step synthesis, discuss whether your team needs a tighter profile than a general research-grade specification. Also confirm whether the product is supplied as a neat material or with any declared residual solvent or stabilizing component.
Ask how the material is packed for the requested quantity and how the supplier recommends storing it. Packaging should protect the material from contamination and be suitable for international transport and your receiving procedure. Your own EHS team should review the supplier’s safety documentation and establish handling controls appropriate to the site.
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Price, MOQ, and lead time are normally dependent on quantity, batch status, packaging, destination, and whether the material is available from stock or requires production scheduling. I do not recommend using an unqualified fixed price or delivery promise as a purchasing benchmark. Instead, request a written quotation that states quantity, Incoterms where relevant, document package, validity period, and estimated dispatch timing.
For 4-Ethylphenylboronic acid, the most useful quotation is one that separates product cost from the assumptions behind it. A small research pack, a development quantity, and a larger repeat order may each have different unit economics. In addition, analytical documentation, special packaging, export requirements, and destination can influence the final commercial proposal.
MOQ should be evaluated against your consumption forecast and material stability plan. Ordering more than the project can use may create avoidable storage and retest obligations, while ordering too little may increase the risk of repeated qualification work. I recommend asking for tiered quantities, estimated lead time for each tier, and the conditions under which a repeat batch can be supplied.
A capable supplier should provide more than a product name and a nominal price. I suggest evaluating the supplier against the following practical questions:
At Maison Chemical, we approach these questions as part of the B2B sourcing process. We can review your requested quantity, target specification, packaging preference, destination, and document needs before preparing a quotation. Where a project has special requirements, I recommend sharing them early so that availability and quality expectations can be assessed together rather than after an order is placed.
One common mistake is selecting solely by the lowest unit price without reviewing the batch documentation. Another is confusing 4-Ethylphenylboronic acid with a similarly named isomer or another ethyl-substituted aromatic boronic acid. A third is failing to confirm whether the quoted lead time refers to stock availability, production completion, or estimated dispatch.
Buyers should also avoid assuming that a single successful laboratory reaction proves long-term supply suitability. Qualification should consider analytical consistency, packaging, communication, and the supplier’s ability to support repeat demand. These checks are especially important when the intermediate becomes part of a regulated, customer-facing, or time-sensitive development program.
Prepare an inquiry containing the product name, CAS number 63139-21-9, required quantity, target purity, intended use, destination, preferred packaging, and document requirements. Ask for the current COA, SDS, availability status, MOQ, lead time, and commercial terms. If your project has a critical impurity limit or a special analytical method, include that information in the first message.
After reviewing the quotation, compare suppliers on total sourcing risk rather than price alone. Confirm the identity and specification internally, approve the sample or batch according to your procedures, and retain the documentation for future repeat orders. This process gives your team a more reliable basis for deciding whether the material is suitable for research, development, or ongoing procurement.
The best way to buy 4-Ethylphenylboronic acid CAS 63139-21-9 is to combine verified identity, fit-for-purpose specifications, documented batch quality, and clear commercial terms. Its role as an aryl boronic acid makes it relevant to a range of synthetic chemistry applications, but actual suitability must be demonstrated in your own reaction and quality system. Maison Chemical can help you evaluate the technical and supply requirements before quotation.
To begin, send us your required quantity, target specification, delivery destination, and documentation expectations. We will use that information to assess the appropriate supply option and provide a practical B2B quotation for 4-Ethylphenylboronic acid CAS 63139-21-9.
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