Stax capsules, utilizing Seitz™ high performance depth filter media and the patented Supradisc II module design, are well suited for demanding prefiltration and clarification biopharmaceutical applications. This ready-to-use platform streamlines your process filtration applications. Stax disposable depth filter capsules increase process efficiencies and address the needs for simplicity, safety, speed, and intuitive operation. Optimized with a small foot print design, the Stax platform makes for an easy to handle and operate process step.
Scalable in size and performance to meet lab, pilot and process needs, Stax disposable capsules enable greater flexibility and ease of use than traditional depth filter technology. With three interchangeable capsule sizes ranging from 0.25 m2 to 2.0 m2 (2.70 ft2 to 21.5 ft2). Stax capsules permit incremental increases in process fluid volume and filter area through the use of this modular design.
The Most Versatile Disposable Depth Filter Platform Placed into one of three different sized chassis, single use Stax capsules eliminate the use of stainless steel housings which require costly cleaning and cleaning validation. Stax system chassis are designed for assembly and use by a single operator and provide a logically conceived disposable platform in which the operator can load, operate and unload in an ergonomically designed vertical orientation. The ability to operate with two different media grades in one chassis (serial filtration) further improves the flexibility and economy of operating the Stax platform. With simple, straight forward and familiar features, the Stax platform eliminates the risk of error or mishap and enables greater process success. Integrating Allegro platforms into a comprehensive single-use system will further maximize the overall benefits of implementing a single-use strategy and the Stax platform.
Features Benefits Low hold-up volume Greater product recovery and lower post use rinse volume requirements than traditional modules and housings. Post use blow down in forward or reverse flow direction are possible. Seamless linear scalability Greater flexibility and assurance of process success from <1L to 20,000+ L Scalable through Pall’s entire line of scale-up devices (SupraCap™ 50 and SupraCap™ 100 capsules) as well as traditional Supradisc I and Supradisc II modules. Provides assurance of meeting process design and requirements. Minimized risk The Stax capsules are based upon the outstanding design of the Supradisc II modules, which provides benefits in process stability due to their high mechanical robustness. No housings Easier to use and manipulate while eliminating operator safety issues. Completely disposable Eliminates need for cleaning and cleaning validation. Encapsulated design Reduces operator exposure to potential biohazards. Intuitive operation Reduces operator training and increases time to acceptance. Small footprint Enables use in close proximity to other equipment and reduces cost to install.
Benefiting from the Supradisc II mechanically robust module design, the Stax capsules provide stable filtration results batch to batch. Through the use of interlocking and welded dual drainage plates, this robust module design is able to provide the structural integrity necessary for:
Unobstructed process flow Consistent filtration results Minimized risk to filter media ruptures due toreverse pressure Minimized risk of damage due to shipping and handling Seitz™ depth filter media available in Stax capsules:
Seitz™ P-series depth filter sheets were specifically developed for the strict requirements in biotechnological and pharmaceutical industries. Manufactured with stringent in-process control methods assures consistent filtration quality, a very high purity of filter medium, and alignment with the requirements of the pharmaceutical industry. For further information, please reference Pall data sheet USD 2205 or validation guide USTR 2366.
Seitz™ HP-series depth filter sheets are comprised of two distinct layers of Seitz™ P-series depth filter sheets; a coarser layer upstream followed by a finer layer downstream. These performance-enhanced depth filter sheets have been designed for use in low viability, high solids containing applications. As small shifts in process conditions can cause dramatic differences in filtration requirements, the flexibility of combining any combination of P-series media in an HP format allows for improved process optimization. For further information, please reference Pall data sheet USD 2335 or validation guide USTR 2404.
Seitz™ Bio-series depth filter sheets are specially developed from highly purified natural and modified cellulose fibers and contain no inorganic materials such as diatomaceous earth (DE), perlite or glass fibers. The lack of these inorganic substances significantly reduces the levels of ash and heavy metal extractables. For further information please reference Pall data sheet USD 2201.
Bottom up Top down Bottom in/bottom out In series
Simply using the uniquely designed manifold kits provides complete flexibility in your process design. Appropriate for use in primary and secondary filtration steps, as well as post-precipitation clarification, in applications such as:
Mammalian cell cultures Yeast E.coli lysates and refolds Vaccines Blood plasma proteins and serum Media
The Pall Stax capsules are available in a wide array of advanced pharmaceutical-grade Seitz™ depth filter media. Supported through comprehensive validation guides, Seitz™ depth filter media meets the highest pharmaceutical standards for:
Quality Lot-to-lot consistency Manufacturing control Low extactable content Low endotoxin content
Stax capsules utilizing Seitz™ high performance depth filter media and the patented Supradisc II module design, are ideally suited for demanding prefiltration and clarification biopharmaceutical applications, increasing process efficiencies and addressing the needs for simplicity, safety, speed, and intuitive operation
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