2-Chlorophenylboronic acid CAS 3900-89-8 is an aromatic boronic acid used primarily as a building block in organic synthesis, especially palladium-catalyzed Suzuki–Miyaura cross-coupling. Its molecular formula is commonly represented as C6H6BClO2, with a molecular weight of approximately 156.38 g/mol. I recommend that B2B buyers confirm identity, assay, water content, residual solvents, packaging, and shipping conditions before placing a bulk order, because these factors can directly affect reaction performance and material handling.
Please visit our website for more information on this topic.
At Maison Chemical, I support buyers who need 2-Chlorophenylboronic acid for pharmaceutical intermediates, agrochemical research, specialty chemicals, and laboratory or process development. The correct purchasing decision depends not only on price, but also on the required purity grade, batch documentation, supply continuity, and compatibility with the buyer’s synthetic process.
This guide is intended for procurement teams, process chemists, research organizations, pharmaceutical manufacturers, agrochemical developers, and chemical distributors evaluating 2-Chlorophenylboronic acid CAS 3900-89-8. It is also useful for buyers moving from gram-scale development to kilogram-scale production. I focus on practical questions: what the product does, which specifications matter, how to evaluate suppliers, and what information to include in an inquiry.
2-Chlorophenylboronic acid contains both an aryl chloride substituent and a boronic acid functional group. The boronic acid group can participate in carbon–carbon bond formation with suitable aryl or vinyl halides under Suzuki–Miyaura coupling conditions. The chlorine substituent may remain available for further chemical transformation, depending on the reaction system and process design.
Because reactivity depends on the substrate, catalyst, base, solvent, temperature, and work-up procedure, I do not recommend treating the compound as a universal drop-in reagent for every coupling process. Buyers should evaluate the material against their own reaction route and define acceptable impurity limits before approving a supplier. A small-scale confirmation batch can be useful when the material is being introduced into a new process.
Commercial offers may differ in purity grade, analytical documentation, packaging format, and supply scale. Some buyers require a research-grade material for route screening, while others need a controlled specification for process development or manufacturing. The product identity should remain consistent, but the release criteria and documentation package may vary between suppliers.
| Parameter | What Buyers Should Confirm | Why It Matters |
|---|---|---|
| Product identity | 2-Chlorophenylboronic acid; CAS 3900-89-8; formula and molecular weight | Reduces the risk of ordering an isomer or incorrectly identified material |
| Assay or purity | Release limit, analytical method, and representative result | Impurities may influence yield, selectivity, and downstream purification |
| Water content | Test method and acceptable limit | Boronic acids can be sensitive to moisture-related handling and weighing concerns |
| Residual solvents | Solvent profile and applicable limits | Important for regulated, scale-up, and downstream applications |
| Packaging | Container type, net weight, seal, labeling, and secondary protection | Supports safe storage, traceability, and transport integrity |
For many synthetic applications, buyers may request a purity target such as 98% or higher, but the correct limit should be determined by the process owner rather than assumed for every application. I can discuss whether a standard specification, a tighter internal specification, or a customized testing package is more appropriate. Buyers should also ask whether the quoted assay is reported on an as-is basis or corrected for moisture or other measured components.
2-Chlorophenylboronic acid can serve as an aryl component in the preparation of substituted biaryl structures and other intermediates. In pharmaceutical development, the buyer normally needs strong lot traceability, consistent analytical results, and clear impurity information. The final selection should be based on the route’s sensitivity to catalyst poisons, inorganic residues, moisture, and related organic impurities.
The compound may also be evaluated in the synthesis of specialty intermediates, crop-protection research compounds, and functional aromatic molecules. In these applications, the most important requirement may be reproducibility across several development batches rather than the lowest initial price. I recommend sharing the intended scale and reaction stage with the supplier so that packaging and quality discussions reflect actual process needs.
During scale-up, a material that performs well at laboratory scale must also be available with reliable batch consistency and practical handling characteristics. Buyers should compare the supplier’s ability to provide repeat lots, retain samples, certificates of analysis, and technical responses. If the route is still being optimized, a smaller qualification quantity may be preferable before committing to a larger shipment.
Link to Maison Chemical
I suggest evaluating suppliers in five stages. First, confirm chemical identity and intended use. Second, define the minimum quality requirements, including assay, water, residual solvents, and any route-specific impurities. Third, request documentation and a representative certificate of analysis. Fourth, compare packaging, logistics, lead time, and commercial terms. Finally, approve the supplier only after the sample or first lot meets the buyer’s internal evaluation criteria.
One common mistake is selecting a supplier solely from a nominal purity number. Two materials with similar assay values can differ in moisture, residual solvents, particle characteristics, or trace impurities that affect a sensitive reaction. Another mistake is requesting a price without stating the required quantity, destination, packaging, and documentation, which can make quotations difficult to compare.
The delivered cost of 2-Chlorophenylboronic acid depends on quantity, specification, packaging, production status, destination, and shipping terms. A laboratory pack and a production-oriented shipment should not be compared as if they have the same cost structure. For a meaningful quotation, I recommend providing the target quantity in kilograms, desired delivery date, destination country, purity requirement, and whether a sample or pre-shipment documentation is needed.
Minimum order quantity and lead time can vary by stock status and production planning. Rather than assuming a fixed lead time, buyers should request a current estimate for the exact quantity and specification. If the material is needed for a scheduled campaign, early communication is important because analytical release, export documentation, and transport arrangements may require additional time.
Packaging should be selected according to order size and handling requirements. Buyers may compare formats such as 1 kg, 5 kg, or 25 kg only when those formats are actually available and suitable for the product. I can help review the practical balance between container size, repeated opening, warehouse handling, and shipment protection, while the final packaging decision should follow the buyer’s safety and quality procedures.
A capable supplier should be able to provide clear product identification, a current certificate of analysis, a safety data sheet, appropriate commercial documentation, and a defined contact for technical or order questions. Buyers should ask whether the quoted specification is standard or customized and whether the reported data represent the actual shipping batch. It is also reasonable to request clarification on retest or shelf-life information where applicable.
At Maison Chemical, I approach 2-Chlorophenylboronic acid sourcing as a specification-matching process rather than a simple price transaction. I can help buyers organize their requirements around identity, purity, quantity, packaging, documentation, and delivery destination. Where the application is technically sensitive, I recommend exchanging the intended use and key acceptance criteria before finalizing the quotation.
Our support can include product information review, quotation preparation, packaging discussion, document coordination, and communication about available supply plans. I do not recommend making a purchase decision from a generic product name alone; the buyer and supplier should confirm the exact commercial and quality requirements for each order.
The best way to purchase 2-Chlorophenylboronic acid CAS 3900-89-8 is to match the supplier’s documented material specification with your process requirements before comparing total cost. I recommend starting with a structured inquiry, reviewing the certificate of analysis and SDS, and qualifying a representative sample or initial lot when the compound is important to reaction performance. This approach can reduce avoidable sourcing and scale-up risk.
To request a quotation from Maison Chemical, please provide your required quantity, purity target, packaging preference, destination, intended application stage, and delivery schedule. I can then help clarify suitable specifications, available supply options, documentation, and the next steps for sample or bulk purchasing discussions.
Are you interested in learning more about 2-Chlorophenylboronic acid CAS 3900-89-8? Contact us today to secure an expert consultation!